Simon LEIRIS

Simon LEIRIS

R&D Project Manager - Synthetic and Medicinal Chemistry, Antabio
 

Currently employed at Antabio

Previous: Pharmaleads, Institut de Chimie des Substances Naturelles (ICSN) - CNRS, Biodesign Institute - Arizona State University (USA)

Experiences

R&D Project Manager - Synthetic and Medicinal Chemistry

At Antabio

From October 2013 to Present
Development of small molecule compounds for the treatment of MDR gram-negative bacteria: - Design, synthesis and development of novel antibiotics adjuvants to enhance the effectiveness of existing antibiotics - Supervision and management of new research projects - Development of API's new...
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R&D project manager - Chemistry

At Pharmaleads

From June 2010 to March 2013
Design, synthesis and development of metalloproteases inhibitors in the field of endogenous analgesia and antidiarrhea - Supervision and management of new research projects: Design, computational visualization (Discovery Studio 3.1) and docking (Gold 5.1) of novel therapeutic targets - Multi-step...
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Research Engineer - Chemistry

At Institut de Chimie des Substances Naturelles (ICSN) - CNRS

From June 2009 to May 2010
Design and synthesis of Calcium Sensitive Receptor antagonists, derivatives of Calhex231 (treatment against osteoporosis)
 

Research Associate - Chemistry

At Biodesign Institute - Arizona State University (USA)

From February 2007 to May 2009
- Synthesis of natural Topopyrones and analogues as potential Topoisomerase I and II inhibitors (antitumoral agents) - Design and synthesis of Verticipyrone analogues as potential mitochondria complex I inhibitors (antiparasitic agents)
 

Skills

 
  • 3D Modeling
  • Analytical chemistry
  • Docking
  • Medicinal chemistry
  • Organic chemistry
  • Pharmaceuticals
  • Project Management

Langues parlées