Université de Bourgogne / INSERM U866
- Maitre de Conférences des Universités
2005 - maintenant
- Ecole Doctorale E2S : La PCR quantitative et ses applications dans vos projets de recherche : TD 4h
- M2R Signalisation Cellulaire et Moléculaire (Cours Magistral et Genome Editing; Transgenèse Animale : 7h)
- M2 Pro Management de l'Innovation en biotechnologies : CM 3h Applications de la (RT)qPCR dans l'industrie agro-alimentaire, en science forensique, clinique,....
- Master I Biochimie/Biologie Moléculaire: Biotechnologies et Génie Génétique; CM: 15h)
- Master 1 Biochimie - Biologie Moléculaire; DNA Chip, Re-Chip, Chip-On-Chip, ATAC Seq, FAIRE Seq, RNA Seq (CM "OMICS": 4h)
- L3 BBM - TD de Pharmacocinétique (6h)
- L3 BBM - TD Préparation à la Vie Professionelle
- L3 BCP - TD Biologie Moléculaire (8h)
- L3 Pro CTCBM: TD Bio-Informatique (4h)
- L3 Pro CTCBM : TD Anglais Scientifique (7h)
- IUT DUT Génie Biologique 2 ABB - TD Bio-Informatique (6h)
Academic Editor for PPAR Research (IF=4,2) depuis 2011: https://www.hindawi.com/journals/ppar/editors/
Rapporteur des thèses suivantes:
The Role of Angiopoietin-like 4 (ANGPTL4) in Chemoresistance and Autophagy During Epithelial-Mesenchymal Transition (EMT); 2018, by Maegan LIM MIANG KEE, Nanyang Technological University (NTU), Singapour; PMID: 30342537.
The Role of Peroxisome Proliferator–Activated Receptor β/δ in Colorectal Cancer; 2018, by Eddie Han Pin TAN, NTU, Singapour; PMID: 29367760.
The Role of Fibroblasts in Cancer Progression, Therapy Resistance and Field Cancerization; 2017, by Jeremy SOON KIAT CHAN, NTU Singapour; PMID: 28892046, PMID: 28102840.
The role of angiopoietin-like 4 in cancer metastasis, 2015, by Zi Qiang TEO, NTU, Singapour; PMID: 28745316.
Angiopoietin-like 4 as a biomarker and therapy target for acute lung damage; 2015, by Li LIANG, NTU, Singapour; PMID: 31164474.
Examinateur de thèse:
Mort cellulaire et modulation du clivage de la cadhérine N par un agoniste de PPARβ/δ dans un modèle de cancer de la vessie par Adeline PECHERY (Besançon, 2016)
Régulation du métabolisme secondaire de l'arginine et de la cystéine par l'acide alpha-linolénique. Implication dans la physiopathologie du syndrome métabolique par Najoua GUELZIM AgropParis Tech (2011)
Publications:
Li et al., Antibody Treatment Against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia, mBio, 2019
Lebrun et al., Enteroendocrine L Cells Sense LPS After Gut Barrier Injury to Enhance GLP-1 Secretion
Cell Reports, 2017
Janssen et al., Modulation of the Gut Microbiota Impacts Nonalcoholic Fatty Liver Disease: A Potential Role for Bile Acids, Journal of Lipid Research, 2017
Nguyen et al., Lipopolysaccharides-mediated Increase in Glucose-Stimulated Insulin Secretion: Involvement of the GLP-1 Pathway, Diabetes, 2014
Mandard and Patsouris, Nuclear Control of the Inflammatory Response in Mammals
PPAR Research (Hindawi Publishing Corporation), 2013
A Role for the Peroxisomal 3-ketoacyl-CoA Thiolase B Enzyme in the Control of PPARα-mediated Upregulation of SREBP-2 Target Genes in the Liver
Biochimie (Elsevier), 2011
Arnauld et al., Modulation of the Hepatic Fatty Acid Pool in Peroxisomal 3-ketoacyl-CoA Thiolase B-null Mice Exposed to the Selective PPARalpha Agonist Wy14,643
Biochimie (Elsevier), 2009
Mandard et al., Glycogen Synthase 2 Is a Novel Target Gene of Peroxisome Proliferator-Activated Receptors
Cellular and Molecular Life Sciences, 2007
Mandard S et al., The Fasting-Induced Adipose Factor/Angiopoietin-Like Protein 4 Is Physically Associated With Lipoproteins and Governs Plasma Lipid Levels and Adiposity
The Journal of Biological Chemistry, 2006
Genolet R. et al., Promoter Rearrangements Cause Species-Specific Hepatic Regulation of the Glyoxylate Reductase/Hydroxypyruvate Reductase Gene by the Peroxisome Proliferator-Activated Receptor Alpha
The Journal of Biological Chemistry, 2005
Zandbergen et al., The G0/G1 Switch Gene 2 Is a Novel PPAR Target Gene
Biochemical Journal, 2005
Patsouris et al., PPARalpha Governs Glycerol Metabolism
Journal of Clinical Investigation, 2004
Mandard et al., Peroxisome Proliferator-Activated Receptor Alpha Target Genes
Cellular and Molecular Life Sciences, 2004
Mandard et al., The Direct Peroxisome Proliferator-Activated Receptor Target Fasting-Induced Adipose Factor (FIAF/PGAR/ANGPTL4) Is Present in Blood Plasma as a Truncated Protein That Is Increased by Fenofibrate Treatment
The Journal of Biological Chemistry, 2004
Kersten S et al., The Peroxisome Proliferator-Activated Receptor Alpha Regulates Amino Acid Metabolism
The FASEB Journal, 2001
Kersten et al., Characterization of the Fasting-Induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-Activated Receptor Target Gene
The Journal of Biological Chemistry, 2000
Denis et al., Nuclear Localization of a New C-Cbl Related Protein, CARP 90, During in Vivo Thymic Apoptosis in Mice
Cell Death and Differentiation, 1999
