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Xavier LECLERC, PHD

Boufféré

Electionseuropéennes 2024

RETROUVEZ GRATUITEMENTLe résultat des européennes à Nantes ainsi que le résultat des européennes en Loire-Atlantique.

En résumé

Mes compétences :
Project managment
Quality Control
Analytical development
R&D
Bioproduction
Development of expression systems
Viral vectorology
Biotechnology
Gene transfer
Genome editing
Intellectual property and research valorisation
Education (teaching)

Entreprises

  • Clean Cells - Geneticist - Head of Gene Therapy & R&D Project Manager

    Boufféré 2015 - maintenant QUALITY CONTROL for GENE THERAPY, GENOME ENGINEERING and BIOPRODUCTION

    Management of activities dedicated to viral vectors quality control

    - Scientific projects steering
    - Viral vectors Quality Control
    - Development and validation of analytical assays according to EP, USP and ICH and in compliance with GLP/GMP
    - Viral vectors bioproduction
    - Reporting to scientific committees
    - Assistance to Business Unit

  • Tennis Fauteuil Riez Océan Association (TFRO) - Member of the Administration Committee

    2014 - maintenant Member of Tennis Fauteuil Riez Océan Association (TFRO) at Saint Hilaire de Riez (France)

    TFRO key figures:

    - Tennis Handisport promotion
    - Organisation of Tennis Handisport tournaments (France championships 2014 and 2015, Open tournaments)
    - Awards: Champion of France Team (2014, 2015 and 2016)
    - Player: Stéphane Houdet (rank: world n°1)

  • Tennis Club Riez Océan Association (TCRO) - Chief Administration Officier

    2014 - maintenant CAO at Tennis Club Riez Océan Association (TCRO) at Saint Hilaire de Riez (France)

    TCRO key figures:

    - Practice and teaching tennis (leisure and competition)
    - 3 full-time employees and seasonal/initiators, over 200 licensees
    - Open tournaments organisation

  • Institute of Biotherapies (in partnership with Cellectis) - Project Leader

    2009 - 2014 GENOME ENGINEERING, GENE THERAPY, VECTOROLOGY & BIOPRODUCTION
    - Scientific projects steering
    - Meganuclease-driven genome engineering
    - Development of innovative gene expression systems for the characterisation of engineered nucleases
    - Duchenne Muscular Dystrophy (DMD) biology
    - Development of optimized production processes for lentiviral vectors biomanufacturing
    - Development of de novo purification processes for new lentiviral vectors pseudotypes biomanufacturing
    - Development of a new lentiviral vector pseudotype for the generation of Sf9 producer cell lines for the large-scale biomanufacturing of AAV-based vectors (baculovirus system)
    - Management of a lentiviral vector production unit (BSL2)
    - Development of analytical assays
    - Logistical and operational management
    - Staff management and training activities
    - Budget and documentation management
    - Reporting to scientific committees
    - Communication and teaching activities
    - Scientific intelligence

  • Higher Studies Practical School (Ecole Pratique des Hautes Etudes, EPHE) - Paris-Sorbonne University - Invited Lecturer

    2008 - 2015 - Human genetics courses - Genome engineering, gene and cell therapies (2nd year of master degree)

  • Généthon - PhD Student

    Ivry 2004 - 2008 Evaluation and optimization of gene correction strategies
    Thesis director: Dr Olivier Danos

  • University of Versailles - Assistant Lecturer (Instructorship)

    2004 - 2007 Courses: Molecular and cell biology, formal and fundamental genetics (BSc level)

  • Généthon - MS Student

    Ivry 2002 - 2003 QC & Analytical Development in Dr Muriel Audit laboratory (henceforth Genosafe)

    - Development and validation of a method for the quantification of integrated lentiviral vector genomes and measurement of transgene expression levels using RT-qPCR assays

Formations

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