Menu

Christian AIRIAU

Marly-le-Roi

En résumé

An expert in data analysis and process modeling with over 10 years experience in the pharmaceutical industry, trained in chemometrics to PhD level.

• Proven success as team manager and matrix leader, aligned with GSK values of Leading Delivery.
• Demonstrable strengths in strategy development, problem solving and stakeholder management.
• Recognised technical expert in data analysis within and outside GSK.
• Strong track record on project support applications with clear associated business benefits.
• Confident communicator with leadership experience in international environments, in R&D & GMS
• Recognized industrial expert in the field of modeling with regulatory agencies


Mes compétences :
Data analysis
Strategy Development
Statistical Process Control
Multivariate Analysis

Entreprises

  • GlaxoSmithKline - Research and Development Chemometrics Manager

    Marly-le-Roi 2008 - maintenant GlaxoSmithKline - UK then US since 2011: Research and Development
    Chemometrics Manager

    * Leadership responsibilities

    * One chemometrician as direct report ;
    * Matrix leader on data analysis activities for 3 late phase projects ;
    * Leader of the Chemometrics Technical Focus Network (CTFN) with 110 members ;
    * R&D representative for the negotiation of global license software renewal


    * Development of the Process Modeling strategy across GSK

    * Steering team member, driving propositions on empirical/mechanistic modeling activities ;
    * Matrix team leader for the Modeling Ways of Working initiative

    * Detailed proposal defining project team expectations for modeling activities ;
    * Close collaboration with key modeling function leaders (Engineers, PAT, Q-Sci)

    * Development and implementation of the Multivariate Analysis strategy in PD

    * Roll out of the MVA strategy on late phase assets in the UK and US ;
    * Structured Change Management approach to introduce new ways of working with governance boards and project teams ;
    * Implementation of an MVA project map: project tracking across the current portfolio


    * Direct project support

    * Lead chemometrician on site for multiple late phase projects ;
    * Core contributor to critical Root Cause Analysis activities;
    * Substantial workpackages supporting teams' control strategy and regulatory filings


    * External advocacy with Regulators and leading Academic groups

    * Established connections with FDA stakeholders in the field of QbD/modeling ;
    * Collaborations with cutting edge academic groups Internationally (EU/US)

    Co-author of the ASTM guideline on Multivariate Analysis

  • GlaxoSmithKline - Global Manufacturing & Supply Technical Development Manager

    Marly-le-Roi 2007 - 2008 * Managed a team of five engineers, responsible for the PAT applications on site ;
    * Implemented and maintained 11 on-line applications ;
    * Aligned PAT modeling TechTransfer process between R&D and GMS ;
    * Key achievement: Implementation of an NIR application for solvent recovery providing a cost avoidance of $1.2M for the Quality Road site.

  • GlaxoSmithKline - Team Leader

    Marly-le-Roi 2005 - 2007 * Managed a team of four scientists ;
    * Oversaw the implementation of PAT applications on site (laboratory - pilot plant) ;
    * Participated in the development of the PAT strategy for the group, integration to Quality by Design and Design Space initiatives ;
    * Key achievement: 25% reduction in cycle time from specific reaction step.

  • GlaxoSmithKline - PAT / Chemometrician expert

    Marly-le-Roi 2002 - 2005 * Developed and implemented over 20 PAT applications (laboratory - pilot plant) ;
    * Responsible for the first PAT project transferred to GMS (Retapamulin) and its integration into the NDA file. ;
    * Introduced and deployed Multivariate Statistical Process Control (MSPC) in GSK ;
    * Key achievements: reaction time optimization using Mid-IR allowing a further two batches to be produced a week, i.e. 5% productivity increase.

  • SERVIER Laboratories - Analyst

    Suresnes 1996 - 1998 Responsible for pharmacokinetics analysis using HPLC and LC-MS/MS

Formations

  • University Of Bristol (Bristol)

    Bristol 1998 - 2002 PhD - Development of Chemometric techniques to hyphenated chromatography

    PhD supervisor: Pr Richard G Brereton

  • Institut National Agronomique De Paris Grignon

    Paris 1995 - 1996 Diplome d'etudes approfondies (DEA)

    Chimie Analytique & Chimiometries

    Premiere introduction a la Chimiometrie (Analyse multivariee). Stage de DEA effectue sous la supervision de Pr Douglas Rutledge.

  • Université Nantes

    Nantes 1990 - 1995 Master of Science

Réseau

Annuaire des membres :