Julien TAILLEMITE

En résumé

Entreprises

• Novartis - Formulation and Process Scientist Continuous Manufacturing

  RUEIL MALMAISON 2012 - maintenant Continuous Manufacturing Solid Dowstream
  Building up the Continuous Manufacturing processes of solid dosage forms paradigme.

• Novartis Pharma AG - Senior Scientist Continuous Manufacturing Downstream OSD

  RUEIL MALMAISON 2012 - maintenant Continuous Manufacturing Formulation and Process Scientist (Member of the core team in the Solid downstream unit, this group was created in
  Pharmaceutical Development / Technical R&D, building up a Group aiming to develop, internalize and utilize
  Continuous Manufacturing Methodologies and Technologies as novel manufacturing paradigm for
  development, clinical supplies, launches and commercial supplies. My main responsabilities are :
  - Develop the technology knowledge on continuous manufacturing technologies. ;
  - Drive formulation development of assigned project. ;
  - Drive technology assessment. ;
  - Support equipment qualification IQ lead on OQ.

• Novartis AG (Basel) - Formulation Scientist Solid Dosage Forms

  2006 - 2012 Formulation Scientist in Pharmaceutical Development.
  Development of solid dosage forms (melt extrusion, wet and dry granulation, tablet, capsules, minitablets, mutilayers tablets, press-coated tablets, solid dispersion...), from the first stage of development lab scale manufacturing process to scale-up and industrial process validation batches.
  
  Formulation Scientist (oral dosage forms) Skyepharma
  Formulation of multi layers tablets Geomatrix® (Modified release dosage forms), and press coated tablets (delayed release tablets).
  Solubilisation technologies: Manufacturing of poorly soluble active drugs nanosuspension SLN® (Solid Liquid Nanoparticles®) with high pressure homogeneisators to increase API solubility.
  Writing in English of formulation development protocol and report.
  Good knowledge of oral excipients and manufacturing processes (WG, DG, DC, tableting, film coating, rotogranulation, wurster, spray drying…)
  
  Publication: Pharmaceutical composition containing coated, floating particles (WO 2006/063858 A1)
  
  Production Technician
  Manufacturing of solid oral dosage forms in GMP/BPF areas.
  Optimization and conception of a granulation liquid system for single pot granulator with microwaves drying system (Turbosphere).
  Quality assistant: batch record first check.
  
  Training in packaging of liquid and semi liquid.
  Packaging Operator.
  
  Main working experiences
  Since October 2006 Scientist in Pharmaceutical development
  2002-2006 Formulation scientist
  2002 Manufacturing technician Oral forms
  1999-2001 Manufacturing technician Oral forms
  1998 Training in packaging of liquid and semi liquid
  Education
  2002 TTPI (Titre de Technicien en Pharmacie Industrielle)
  1998 OTPI (Titre d’Opérateur en Pharmacie Industrielle)
  English: Fluent
  Hobbies: Tennis, snowboard, ski, travelling…

• Novartis Pharma AG - Formulation and Process scientist

  RUEIL MALMAISON 2006 - 2011 Formulation Scientist in Pharmaceutical Development (Novartis Pharma)
  Development of solid dosage forms, from the first stage of development lab scale to pilot and industrial process, pre-validation/confirmation using FMEA and QbD, transfers made in CH, USA, Canada and China.
  Development of Pediatric dosage forms: Dispersible tablet, mini tablet.
  Formulation & development of projects using Hot Melt Extrusion solid dispersion/solution technology.
  Leading the technical part of investment project (Melt extruder apparatus...)
  Strong skills in manufacturing processes (Wet Granulation, Roller Compaction, Dry Blending, tabletting,
  film coating, rotogranulation, wurster, spray drying, melt granulation and extrusion...)
  Publication/Patent:
  - Galenical formulations of Aliskiren and Valsartan (WO/2009/045795)
  

• Skyepharma AG - Formulation scientist

  2002 - 2006 Formulation Scientist of solid dosage forms (SkyePharma AG)®
  Formulation and process development of multi layers tablets Geomatrix ® (Modified release dosage forms),and press coated tablets (delayed release tablets).
  Solubilisation technologies: Manufacturing of poorly soluble active drugs nanosuspension SLN® (Solid Liquid Nanoparticles ) with high pressure homogeneisators to increase API solubility.
  Publication/Patent:
  Pharmaceutical composition containing coated, floating particles (WO 2006/063858 A1)

• Skyepharma - Formulation scientist

  2002 - 2006 Formulation and process development of Modified Realease multi layer tablets (Geomatrix technology)
  Development of Nanotechnology (SLN Solid liquid Nanoparticles)

• Sanofi Synthélabo - Manufacturing Technician

  2002 - 2002 Production Technician
  Manufacturing of solid oral dosage forms in GMP/BPF areas.

• Merck Lipha - Manufacturing technician

  Lyon 1999 - 2001 Production Technician
  Manufacturing of solid oral dosage forms in GMP/BPF areas.
  Optimization and conception of a granulation liquid system for single pot granulator with microwaves drying
  system (Turbosphere).
  Quality assistant: batch record first check.

Formations

• IMT

  Tours 2001 - 2002 TTPI

• IMT

  Tours 2001 - 2002 TTPI

Réseau

• Agnès DHERMAIN - MEURISSET

• David ROQUELET

• Emmanuelle BARTHÉLEMY TAILLEMITE

• Isabelle LEBRUN

• Jack ZERROUK

• Julien MARCHAND

  Les Brasseurs Savoyards (Alby-sur-Chéran)

• Mustapha ABOUSSIF

• Nicolas DEBSKI

• Thomas RICOUR