Marie-Laure MICHEL

En résumé

Entreprises

• Novartis - Research Associate

  RUEIL MALMAISON 2018 - 2018 Test candidate drugs in rodent models of muscular diseases. Pharmacodynamics time course in mice with a human protein. Evaluate cross-reactivity of human protein in mice. Explore subcutaneous and intraperitoneal route at several point. Force experiment in mice for functional testing, compound administration, blood/organ sampling, rodent necropsy, extraction of RNA, RT-qPCR from tissues, in-vitro and in-vivo assay development of models of disease in compliance with animal welfare legislation.

• University of Basel - Research Associate

  2017 - 2018 Oncology Research with focus on the recognition of non-peptidic antigens by T lymphocytes. Cell culture, isolation and culture of primary human and mouse immune cells from blood and tissue, in vitro immune cell assays, cloning, multicolor flow cytometry, molecular biology, transfection with a Lentivirus, transduction, PCR, Western Blot, ELISA, genotyping of mice, miniprep, analyzed, interpreted and communicated complex data.

• Laboratoire de génétique médicale, INSERM - Biology Engineer

  2016 - 2017 in vivo experimentations with mice and rats for avoid kidney disease and diabete. Mice farming, biochemistry, molecular biology

• Cellprothéra - Cell culture technician

  2015 - 2016 in vitro cellular therapy with stem cells and flow cytometry used with R&D tests aiming at starting clinical trial for myocardial infarction patients.

• Confarma France SAS_Division Cosmétiques/ OTC - Cell culture technician

  Paris 2013 - 2015 using in vitro and in vivo tests, cell culture, biochemistry and pharmacology to evaluate the toxicity of drugs and medical devices with GLP and GMP.

• Centre Européen d'étude du diabète - R&D Internship

  2013 - 2013 Stimulation of pancreatic islet revascularization by modulation of HIF-1α pathway with siRNA.

• Laboratoire de Neurobiologie et Pharmacologie cardiovasculaire - Research Internship

  2012 - 2012 Study of LNP199 treatment on cardio-vascular system in rats.

• Laboratoire d’Imagerie et de Neuroscience Cognitive - Research internship

  2011 - 2011 Study of thalamus nucleus lesion on spacial memory in rats.

• Laboratoire de Biophotonique et Pharmacologie - Researchinternship

  2011 - 2011 Study of vascular reactivity on coronary arteries with different treatments.

• Kraft Food - Quality and Security Internship

  2009 - 2009 Quality assurance on several production lines.

Formations

• BD Biosciences

  Paris 2016 - 2016 certification
  
  Certificate of training on flow cytometry for Research and Standardisation,
  Flow cytometry : BD FACSCanto II and BD FACSDIVa 8.0.1

• Faculté De Pharmacie De Strasbourg

  Strasbourg 2011 - 2013 Master Sciences du médicament - Pharmacologie
  
  Master - Drug Sciences major in Pharmacology, good distinction.
  Animal experimentation diploma, level 1.
  Rodent surgery diploma.

• Faculté Des Sciences De La Vie - Université De Strasbourg

  Strasbourg 2010 - 2011 Licence Science du Vivant, spécialité Biologie Cellulaire et Physiologie
  
  Degree - Cellular Biology and Physiology, distinction

• IUT Louis Pasteur (Schiltigheim)

  Schiltigheim 2008 - 2010 DUT Génie Biologique option IAB
  
  Technology degree - Biology Engineer

Réseau

• Andrea LEHMANN

• Anna-Maria ROTOLO

• Ariane MOGHA

• Atlan PATRICK

• Delphine HERRMANN

• Emilie CLER

• Kévin ROHE

• Olga ADAMIEC

• Oriane MITH

• Pauline HABER