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Johnson & Johnson
- Senior Scientist, Cellular and Molecular Pharmacology
New Brunswick
2015 - maintenant
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Pfizer
- Senior scientist
Paris
2014 - 2015
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Cactus Communications
- Freelance Editor, Life Sciences Team
2013 - 2013
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Columbia University
- Associate Research Scientist
2010 - 2014
Development of new biased ligands at the kappa opioid receptor (KOR) - Screening of new chemotypes for the study of the KOR receptor in the etiology of drug
addiction, depression, and pain (Patent pending).
- Medium through-put cell-based fluorescence-based biophysical technologies (BRET) to study
the pharmacological properties of newly synthesized compounds
- Biochemistry (Western blotting), flow cytometry analysis (biomarker assay), and other SAR
studies (molecular biology-based) to investigate the mechanisms and molecular determinants of
ligand bias.
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Research Foundation for Mental Hygiene
- Assistant Research Scientist
2010 - 2014
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Columbia University, New York, NY
- Post-doctoral Research Scientist
2009 - 2010
Research project: Assembly and signaling of the dopamine D2 receptor homomers and heteromers.
* Fluorescent ligands-based HTRF technology, Immunohistochemistry, Drosophila melanogaster.
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IGF, Institute of Functional Genomics, Montpellier, France
- PhD in Molecular Pharmacology
2006 - 2009
Research Project: Crosstalk between the metabotropic glutamate receptor type 1a (mGluR1a) and the gamma-aminobutyric acid type B receptor (GABAB).
* GPCR, Ligand binding, Second messengers assays: cAMP, IP production, calcium increase, Medium through-put biophysical technologies as FRET (HTRF - Strong collaboration with CisBio Bioassays) and BRET, Molecular Biology, Primary cultures of mouse cortical neurons and astrocytes.
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Auris Médical - Inserm U583, Montpellier, France
- Master 2 Research Internship
2006 - 2006
Research Project: Study of the carbonylation of the NMDA receptors within the cochlea after salicylate activation and identification of the carbonylated subunits.
* Introduction to Proteomics, 2D-electrophoresis, Co-immunoprecipitation.
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INM, Neurosciences Institute, Montpellier, France
- Internship
2005 - 2005
Research project: Cytotoxicity and metabolism of the 7β-hydroxycholesterol within the study of the Glioblastom.
* Cellular viability, Akt phosphorylation and Autophagy signaling pathways, Lipid extraction.
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Laboratory of Functional and Evolutionary Parasitology, CNRS, Perpignan, France
- Internship
2003 - 2003
Research project: Identify genes involved in Biomphalaria glabrata resistance/susceptibility towards Schistosoma mansoni and Echinostoma caproni, as well as genes involved in the immune response against these parasites.
