Mes compétences :
Clinical Trial
Emulsion
Excipients
Formulation
Formulation galénique
Galénique
HPLC
Management
Microsoft Project
Microsoft Project Management
Gestion de projet
Entreprises
Robert Mac Bride
- Analyst in Quality Control Laboratory
2007 - 2007• Control at various levels of the production for aerosol and aircare product,
• GC, Karl-Fisher Titration, Acid-Base Titration, pHmetry, Density, Viscosity, Microbiology, IR, Refractometry.
• SAP
Astrazeneca
- Analytical and Formulation scientist
Rueil-Malmaison 2007 - maintenant•Provide high quality analytical and formulation support to Discovery from animal testing to first time in man
•Advise project leaders and other team colleagues on analytical and/or formulation for varied types of formulations (IV , suspension, nano-suspension, solution, solid dosage form)
•Development of tablet/ capsule screening to deliver solid dosage form for phase 1 clinical studies
•GMP formulation and analysis
•Working knowledge of manufacturing challenging clinical formulations (IV and liquid formulations)
•Xcelodose trained and development of filling method for capsule
•Perform analytical testing on drug substance and drug product using standard techniques such as HPLC, particle size measurement, dissolution, XRPD, hardness testing...
•Analytical method development and validation
•Development of stability protocol for drug substance and drug product
Contribution to IMPD/IND and regulatory dossiers
•Project representative with cross functional interaction (Bio-science, Safety study, DMPK, Chemistry, Manufacturing , Clinical, Contractor)
Selection of high quality candidate drugs: selection of drug substance final form and drug delivery technologies
Laboratory coordinator, implementation of 5S and continuous improvement, SHE representative, supervision of lab aids
Innovation facilitator in Pharmaceutical Development initiative
Contribution in student interview process and training
Gerflor
- Chemist in R&D section Innovation
Villeurbanne2006 - 2006• Optimised novel flooring in PVC with the tendencies
• Created new flooring by recycling PVC
Syngenta
- Chemist in Formulation Development
Guyancourt 2004 - 2005• Developped an insecticide in aqueous formulation from business target plan.
• Followed -up of stability with the CIPAC methods (test of emulsion, pH, appearance, size of particle (Malvern), microscopy, viscosity) Analysis: HPLC, GC, TGA.
• Optimised an oil-based Herbicide : antisettling agent, emulsifier system
• Use of statistical design to optimise and reduce cost.
