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Thibaud GERFAUD

Courbevoie

En résumé

Mes compétences :
Chemistry
Synthesis

Entreprises

  • Galderma - Chimiste de développement

    Courbevoie 2012 - maintenant
  • Swiss Federal Institute of Technology (ETH) - Post-Doc

    2011 - 2012 My post-doctoral project involved very different fields of chemistry such as polymer chemistry, biomolecules synthesis and ligation reactions. I developed a practical and scalable synthesis of enantiopure beta-amino acids and worked on a molecular machine behaving as an artificial ribosome.

    Enantioselective, chromatography-free synthesis of β3-amino acids with natural and unnatural side chains

    http://pubs.acs.org/doi/abs/10.1021/op300069n


  • ISCN/CNRS, Prof. Jieping Zhu - PhD

    2007 - 2010 My PhD project involved the development of new transition metal catalyzed heteroannulation processes and their application in total synthesis. In this context, I recently developed an intermolecular domino aminopalladation/C-H activation sequence for the synthesis of Phenantridines and Isoquinolines. I applied another heteroannulation process developed in the laboratory for a total synthesis.

    Protecting-group free total synthesis of Alstoscholarine

    http://onlinelibrary.wiley.com/doi/10.1002/anie.201100257/abstract

    Palladium-Catalyzed Annulation of Acyloximes with Arynes (or Alkynes): Synthesis of Phenanthridines and Isoquinolines

    http://onlinelibrary.wiley.com/doi/10.1002/anie.200804683/abstract

    Unexpected C-C Bond Cleavage: Synthesis of 1,2,4-Oxadiazol-5-ones from Amidoximes with Pentafluorophenyl or Trifluoromethyl Anion Acting as Leaving Group

    http://pubs.acs.org/doi/abs/10.1021/ol202554m
  • Sanofi Aventis - Master's placement

    Paris 2007 - 2007 - Development of new copper and palladium-catalyzed reactions on heterocyclic structures
    - Synthesis and characterization of pharmacologically active compounds for Central Nervous System
  • GlaxoSmithKline - Industrial placement

    Marly-le-Roi 2005 - 2006 Total syntheses of stable labelled molecules within the Isotope Chemistry group

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